Cosmetic ingredient

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID is the INCI name for HEPES, an organic substance also known in scientific work as a Good's buffer. It is not a botanical extract or an oil: it is a defined compound built around a piperazine portion with hydroxyethyl and ethanesulfonic groups.

INCIHY1 products
CAS number
7365-45-9
EC number
230-907-9
Chemical name
4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID: what it is

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID is the INCI name for HEPES, an organic substance also known in scientific work as a Good's buffer. It is not a botanical extract or an oil: it is a defined compound built around a piperazine portion with hydroxyethyl and ethanesulfonic groups.

The full name is common on ingredient lists, while HEPES is the shorter name used more often outside cosmetics. HEPES can take part in the balance between acidic and basic forms in a solution, a feature that makes it useful where pH needs to remain controlled.

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID: what it does in cosmetics

In cosmetics, HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID works as a buffer. In practical terms, it helps prevent abrupt pH shifts in a formula, supporting the intended acidity during preparation and use. This is a formula-stability role, not an active meant to soften skin or cleanse hair.

HEPES is well known in research as a buffer for cell-culture media, where it helps keep pH near the desired range. That laboratory use explains its chemical property, but it does not by itself show a treatment, renewal, or skin-improving effect in a topical cosmetic.

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